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Addressing Alcoholism with Diet and Nutrition
Alcoholism is a very complex problem that is rampant in our society and has many variables that need to be addressed simultaneously. The success rate with mainstream treatment options is poor at best. The nutrition and diet components are rarely...

Buying Nutritional Supplements Online
If you are looking to purchase nutritional supplements, look no further than the World Wide Web. There are millions of businesses based both in the "real" and virtual worlds that hock any type of natural extract or supplement imaginable. These...

Muscle Building Nutrition 101
Correct muscle building nutrition and a quality muscle building diet are often the most neglected parts of a weight training program. Building muscle requires the right nutrition. Make no mistake, it's an essential part of weight lifting...

Nutrition And Mental Function
(NC)-Eating well and getting the vitamins and minerals we need over the course of our lives is important for overall good health. It may also help preserve memory and cognition in the golden years. There is growing evidence to suggest...

Post Workout Nutrition: Secrets to a Ripped, Lean Body
As you've probably heard before, your post-workout meal may very well be your most important meal of the day. The reason is that when you're finished with an intense workout, you're entering a catabolic state where your muscle glycogen is depleted...

 
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Melatonin Melatonin, or 5-methoxy-N-acetyltryptamine, is a hormone produced by pinealocytes in the pineal gland, located in the brain, but also in the retina and GI tract. It is a derivative of the amino acid tryptophan. Melatonin produced in the pineal gland acts as an endocrine hormone since it is released into the blood. On the other hand, melatonin produced by the retina and the GI tract is considered a paracrine hormone. Melatonin helps regulate sleep-wake or circadian rhythms. Normally, production of melatonin by the pineal gland is stimulated by darkness and inhibited by light. Melatonin can suppress libido by inhibiting secretion of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the anterior pituitary gland -- especially in mammals that have a breeding season when daylight hours are long, such as sheep. Nobel Prize laureate Julius Axelrod performed many of the seminal experiments elucidating the role of melatonin and the pineal gland in circadian rhythms. Beta blockers decrease nocturnal melatonin release. Melatonin is synthesized by various plants such as rice and ingested melatonin was shown to be capable of reaching and binding to melatonin binding sites in the brain of mammals. In recent times, melatonin has become available as a drug and a dietary supplement. It appears to have some use against insomnia and jet lag. Melatonin is a powerful antioxidant which can easily cross cell membranes. It has been studied for the treatment of cancer, immune disorders, cardiovascular diseases, depression, seasonal affective disorder, and sexual dysfunction; no apparent benefit in these has been found. To synthesize melatonin, serotonin is converted to N-acetylserotonin by the enzyme 5-HT N-acetyltransferase. N-acetylserotonin is then converted to melatonin by the enzyme 5-hydroxyindole-O-methyltransferase. See serotonin for details on how tryptophan is converted to serotonin. Melatonin has been shown to increase the lifespan of mice by 20% in some studies

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